Patient Information:

• Name: Aleksandre Tarasenko
• Diagnosis: Parkinson's Disease
• Date of Birth (D.O.B): March 5, 1951
• Gender: Male
• Country: Russia

Treatment: Minimally Invasive Brain Surgery (Functional Stereotaxy), daily IV neurological nutrient medications and physical/occupational therapy, Traditional Chinese Medicine.

History:
Mr. Aleksandre Tarasenko is a 65-year-old Russian citizen living in Germany. He began experiencing Parkinson's symptoms nine years ago, significantly impacting his life and work. Despite trying various medications, he couldn't control his condition. After learning about Beijing Puhua International Hospital online and undergoing a pre-admission evaluation with the help of a medical consultant, Aleksandre was admitted to the hospital according to his scheduled appointment.

Preoperative Condition:
Aleksandre had a good general physical condition with normal muscle strength and muscular tension. However, notable tremors were present in his left upper and lower limbs, especially in his left hand. An MRI of his brain revealed lacunar infarction and punctuate ischemia. A PET-CT scan confirmed the diagnosis of Parkinson's disease.

Treatment Course:
Aleksandre underwent a right frontal stereotactic operation, with daily administration of neurotrophic factors described in the historical report; neural-cell activation is not established by this case, accompanied by daily physical therapy, occupational therapy, and Traditional Chinese Medicine treatments.

Postoperative Condition:
Following the stereotactic operation for Parkinson's Disease, Aleksandre's tremors in his left limbs completely disappeared. The historical account reports medication discontinuation and patient satisfaction. This is not a treatment recommendation; prescribed medication should only be changed with the treating clinician. Prior to surgery, Aleksandre worked as a lawyer but struggled due to his tremors. Postoperatively, he regained the ability to work without limitations, as he had before developing Parkinson's symptoms.

Patient Information:

• Name: Penny Thomas
• Diagnosis: Parkinson's Disease
• Date of Birth (D.O.B): August 3, 1954
• Gender: Female
• Country: United States

Treatment: Minimally Invasive Brain Surgery (Functional Stereotaxy) with post-operative daily IV neurological nutrients and medications.

Preoperative Condition:
Ms. Thomas, a female patient from the US, suffered from Parkinson's disease for several years. Her symptoms included:

• Uncontrollable shaking and tremors
• Extreme muscle tension and weakness
• Frequent freeze-ups during walking or movement
• Difficulty talking on the phone, reading, writing, eating, brushing hair, getting out of chairs, or getting up from bed independently
• Limited neck mobility

Postoperative Condition (17 Days after Discharge):

• Tremors greatly reduced but still occurred occasionally when concentration was high
• Muscle tension eliminated
• Strength improved, allowing for normal daily activities such as driving and sailing
• Self-confidence restored

Long-term Follow-up:

• 4 Months after Discharge: Penny visited friends and relatives in the US, attended her high school reunion, went horseback riding, and swam with dolphins. The historical account mentions missed medication doses; this is not evidence that missing prescribed doses is safe.
• 1 Year after Discharge: The historical account reports a reduced medication dose. Medication changes require assessment and supervision by the treating clinician. She engaged in various physical activities like gardening, riding horses, swimming, and hiking while maintaining regular rest. She also practiced positive affirmations such as "I'm recovering from Parkinson's."
• 10 Years after Discharge: Penny's condition remained stable.

Patient Information:

• Name: Ah Chay Tan
• Diagnosis: Parkinson's Disease
• Date of Birth (D.O.B): January 1, 1935
• Gender: Male
• Country: Philippines

Treatment: Minimally Invasive Brain Surgery (Functional Stereotaxy) for Parkinson's Disease, along with daily IV medication, neural cell activation and proliferation therapy, Traditional Chinese Medicine (TCM), rehabilitation therapy, and blood pressure management.

Medical History:

Mr. Ah Chay Tan, a 77-year-old male from the Philippines, was admitted to Beijing Puhua International Hospital due to "progressive involuntary tremors of limbs" for over twelve years. His Parkinson's Disease began in 1998 with slight shaking of his right hand, which progressively worsened along with slow gait, deteriorating motor skills, and resting tremor, more severe on his right side.

Preoperative Condition:

• Independent walking but very slowly with flexed posture, mild shuffling steps, and limited arm movement
• Able to write, eat, climb stairs, get in/out of bed, dress/undress independently (albeit slowly)
• Resting tremor, exacerbated by nervousness
• High muscle tone causing stiffness in limbs and trunk, impairing fine movements
• Slurred speech with masklike face upon examination

Treatment Details:

Mr. Tan underwent a stereotactic operation for Parkinson's Disease at BPIH, which included:

• Injections of neural growth factors
• Neural cell activation and proliferation therapy
• Traditional Chinese Medicine (TCM) treatments
• Rehabilitation therapy to improve functional mobility and independence
• Medications for managing blood pressure

Postoperative Condition (Five Weeks After Surgery):

• Speech clearer with increased facial expressiveness and smiling
• Improved flexibility in limbs and trunk, facilitating fine movements and turning over in bed
• Felt stronger with faster walking and more natural arm movements, improved posture
• Reduced tremors in both hands, better control over tremor symptoms

Patient Information:

• Name: Mubarak Alneaimi
• Diagnosis: Parkinson's Disease
• Date of Birth (D.O.B): January 1, 1950
• Gender: Male
• Country: United Arab Emirates

Treatment: Minimally Invasive Brain Surgery (Functional Stereotaxy) for Parkinson's Disease, along with daily IV medication, neurological nutrition support, physical and occupational therapy sessions, Traditional Chinese Medicine (TCM) treatment.

Medical History:

Mr. Mubarak Alneaimi had been living with Parkinson's Disease for three years prior to his current admission. He experienced:

• Tremors on the right side of his body
• Generalized weakness throughout his body
• A heavy sensation in his left leg while walking
• Deteriorating handwriting
• A desire to slow down or reverse the progression of his condition

Preoperative Condition:

• Slowed movements, making it difficult for him to engage in activities he enjoyed, such as fishing
• Inability to walk steadily, even for daily tasks like brushing teeth
• Sleep disturbances with frequent nightmares
• Insecurity while driving due to emotional upset and fatigue
• Reduced ability to exercise compared to before his diagnosis

Treatment Details:

Mr. Alneaimi underwent a stereotactic injection of neural growth factors into his brain as part of his minimally invasive brain surgery for Parkinson's Disease. This was accompanied by:

• Daily IV therapy to manage symptoms and side effects
• Neurological nutrition and protection to support overall brain health
• Physical and occupational therapy sessions to improve motor function, coordination, balance, and independence in daily activities
• Traditional Chinese Medicine (TCM) treatments for supplementary symptom relief and overall well-being

Postoperative Condition:

Even before the stereotactic operation was completely finished, Mr. Alneaimi began to feel improvements in his symptoms. Upon completing the entire treatment plan:

• The account reported symptom improvement, without a stated validated assessment scale
• Further changes would require follow-up assessment and cannot be predicted